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Smad3 (4C9) Mouse mAb

EM1315

規(guī)格：	價(jià)格：
50μL	￥1280.00
100μL	￥1980.00

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Overview

Product name:	Smad3 (4C9) Mouse mAb
Reactivity:	Human, Rat, Mouse
Alternative Names:	hMAD3 antibody, HSPC193 antibody, LDS1C antibody, MADH3 antibody, JV15 2 antibody
Source:	Mouse
Dilutions:	WB? 1:1,000-2,000???? IHC 1:100-200
Immunogen:	Synthetic Peptide
Storage:	PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
Clonality:	Monoclonal
Isotype:	IgG1
Concentration:	1mg/mL
Observed Band:	52kDa
GeneID:	4088
Human Swiss-Prot No:	P84022
Cellular localization:	Cytoplasm,?Nucleus
Background:	Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription.

Western blot analysis of 1) Mouse Brain Tissue Lysate, 2) Rat Brain Tissue Lysate using Smad3（ EM1315）Mouse mAb diluted at 1:2000.
Immunohistochemical analysis of paraffin-embedded Human Liver Carcinoma Tissue using?Smad3（EM1315）Mouse mAb diluted at 1:200.
Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma Tissue using?Smad3（EM1315）Mouse mAb diluted at 1:200.

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